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Introduction
Generic Nexium is a medicine with the active component of Esomeprazole, which is the S-isomer of omeprazole, which combines the S- and R- isomers. The drug is offered in the form of capsule or tablets or a powder in different strengths. It is also called as "the purple pill" since it is a purple capsule having two or three gold rings, based on the potency.
Drug Indications
Generic Nexium is approved for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, Helicobacter pylori (H. pylori) infections and pathological hypersecretory conditions, where there is excess stomach acid. This medicine also prevents stomach ulcers in patients using nonsteroidal anti-inflammatory medicines (NSAIDs), for example ibuprofen.
Drug Contraindications
Nexium should not be administered to patients with known hypersensitivity to any constituent of the formulation or to alternative benzimidazoles.
Dosage
GERD and Erosive Esophagitis
Take the drug once a day, at least one hour before a meal.
For patients having gastroesophageal reflux disease (GERD) symptoms, a 20 mg of Nexium has been approved once a day for four to eight weeks. If it is severe enough which may lead to esophageal erosions, the usual dose is 20 to 40 mg once daily for four to eight weeks. The dose should be followed by 20 mg once daily.
For GERD and erosive esophagitis in children ages 12 to 17, the suggested dose is same as elder patients. Children age 1 to 11 years old, can take 10 mg once daily for up to eight weeks.
Stomach Ulcer Prevention
In stomach ulcer (gastric ulcer) associated with nonsteroidal anti-inflammatory drugs (NSAIDs), patient can take initial dose of 20 mg or 40 mg once a day for up to 6 months.
H. Pylori Treatment
In Helicobacter pylori (H. pylori) patient needs to take two other drugs besides Nexium. He can take amoxicillin 1,000 mg (twice daily), Nexium 40 mg once a day, and clarithromycin 500 mg (twice daily) for ten days.
Pathological Hypersecretory Conditions
Patients with pathological hypersecretory conditions can take 40 mg twice daily.
Mode of Action
Nexium is from a group of drugs known as proton pump inhibitors (PPIs). It reduces the quantity of acid in your stomach by congestion the acid production sites.
Drug Interactions
There are chances for Nexium (esomeprazole magnesium) to interact with many other medications. Some of these possible drugs are: certain antifungals, Clopidogrel (Plavix), Cilostazol (Pletal), Diazepam (Valium), Dasatinib (Sprycel), Mesalamine (Apriso), Digoxin (Lanoxin, Digitek, Lanoxicaps ), Iron supplements or pills, Erlotinib (Tarceva) and some protease inhibitors, such as warfarin (Coumadin, Jantoven).
Side Effects
The use of this drug may lead to some unwanted adverse effects. If you feel any such effects, notify your doctor immediately possible. Only your doctor can settle on if you should continue taking drug. Side effects are diarrhea, abdominal pain and headache.
Warnings & Precautions
Use caution while using Nexium with certain medicines. This drug should not be used in pregnancy. It may cause harm to unborn babies. Talk about the safety of taking drug with your doctor before using the drug.
In patients with severe liver disease, the dose should not exceed a daily dose 20 mg. If you are breastfeeding, stop taking the tablet or stop nursing. It is unclear whether the drug element passes through your milk.
Synonym
Venezuela: Nexium
United States: Nexium
United Kingdom: Nexium
Thailand: Nexium
Switzerland: Nexium
Sweden: Nexium Nexium
Spain: Axiago
Singapore: Nexium
South Africa: Nexiam
Russia: Nexium (Нексиум)
Portugal: Nexium
Norway: Nexium
Netherlands: Nexium
Mexico: Nexium
Malaysia: Nexium Nexium Lucen Esopral
Italy: Axagon
Israel: Nexium
Ireland: Nexium Sompraz Esoz
India: Esomac
Hungary: Nexium
Hong Kong: Nexium
Greece: Nexium
Germany: Nexium
France: Inexium
Finland: Nexium
Denmark: Nexium
Czech Republic: Nexium
Chile: Nexium
Canada: Nexium
Brazil: Nexium
Belgium: Nexiam
Austria: Nexium
Australia: Nexium
Argentina: Nexium
