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Sucralfate is a gastric protective. It straightforwardly restrains pepsin, an enzyme that breaks apart proteins in the existence of stomach acid. It sticks to the surface of ulcers (attaching to bare proteins) and covers the ulcer. As a result the ulcer surface is protected somewhat from further damage by acid and pepsin.
Indication
Sucralfate is used to treat peptic ulcer disease and to avoid periodic ulcers after curing of the ulcer. This drug is also applied to alleviate or check the ulcers associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Sucralfate also is applied in gastroesophageal reflux disease (GERD) patients who have high risk to get ulcers in the esophagus and to avoid ulcers caused by high level of physical stress such as surgery, extensive burns, and overwhelming infection.
Dosage and Administration
To treat active duodenal ulcer, an adult oral dosage of 1 g has been recommended four times per day on an empty stomach.
Antacids may be taken for relief of pain but should be avoided within one-half hour earlier than or after Sucralfate.
Patient may notice improvement in a week or two, but it is vital to continue taking drug for 4 to 8 weeks till remedial has been confirmed by x-ray or endoscopic examination.
An adult oral dosage of 1 g twice a day has been recommended for maintenance dose.
Elderly patient should be administered this tablet with carefulness. A lower starting dose can be considered for them.
Side Effects
Sucralfate tablets are usually less harmful for any adverse reaction. However constipation is the most common adverse and unwanted secondary effect and arises in 1 of every 50 patients using this drug.
Other effects like dizziness, dry mouth, dizziness, back pain, indigestion, or itching may also come about as your body adjusts to the medication. If these reactions continue or aggravate, don't forget to notify your doctor. Patient may experience other effects not listed above.
Report to your physician about all the pills you use prescribed and non- prescribed, particularly if you are taking some antibiotics like doxycycline, quinolones for example (ciprofloxacin), phenytoin, antacids, cimetidine, digoxin, ranitidine, ketoconazole, theophylline and penicillamine etc. Keep away from starting or discontinuing any medication devoid of doctor or pharmacist agreement.
Acquaint with your physician your medical history mainly of: any allergies, stomach/intestinal problems, difficulty swallowing, kidney disease. Before using this medication, tell your doctor if you are pregnant. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.
This drug may lead to dizziness. Alcohol or certain medicines may aggravate these effects. So don't take them while being treated. You should avoid driving or carrying out other possibly hazardous tasks until you know its effect on you. Sucralfate Tablet holds aluminum in it. Before using any new pills, read the label to ensure if it contains aluminum in it. Use it with extreme caution in children; safety and usefulness in children have not been clear.
Storage
Tablets and suspension should be kept at room temperature.